Sporadic cases are the norm for complex disease

Sporadic cases of Legionnaires' disease in the Netherlands.

Sera of 24 patients with an unexplained pneumonia were tested for the presence of antibodies against the Legionnaires' disease bacterium. Fifteen patients had positive serology. The series comprised 12 male and three female patients ranging in age from 17 to 66 years (mean, 51.1 years). All of the patients had a high fever, little or no sputum production, and radiographic evidence of pneumonia....

Border Disease Control Checkpoints: Are They Sufficient for Disease Control? The Present Situation in Thailand

Crohn's disease severity in familial and sporadic cases.

BACKGROUND Having a relative with inflammatory bowel disease increases the risk for Crohn's disease but may also increase its severity in affected patients. AIMS To evaluate the influence of a family history on Crohn's disease course and severity. METHODS 1316 patients followed in the same unit were studied retrospectively. Age at onset, duration of illness, site, and extent of disease were...

Legionnaires’ Disease: Clinicoradiological Comparison of Sporadic Versus Outbreak Cases

BACKGROUND In 2015, New York City experienced the worst outbreak of Legionnaires' disease in the history of the city. We compare patients seen during the 2015 outbreak with sporadic cases of Legionella during the past 5 years. METHODS We conducted a retrospective chart review of 90 patients with Legionnaires' disease, including sporadic cases of Legionella infection admitted from 2010 to 2015...

Pinpointing clusters of apparently sporadic cases of Legionnaires' disease.

OBJECTIVES To test the hypothesis that many non-outbreak cases of legionnaires' disease are not sporadic and to attempt to pinpoint cases clustering in space and time. DESIGN Descriptive study of a case series, 1978-86. SETTING 15 health boards in Scotland. PATIENTS 203 probable cases of non-outbreak, non-travel, community acquired legionnaires' disease in patients resident in Scotland. ...